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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
INPP5D
All Species:
9.7
Human Site:
S971
Identified Species:
21.33
UniProt:
Q92835
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92835
NP_001017915.1
1189
133292
S971
P
P
G
Q
P
P
I
S
P
K
K
F
L
P
S
Chimpanzee
Pan troglodytes
XP_526066
929
104074
T728
N
R
G
L
P
A
R
T
Q
E
S
R
P
S
D
Rhesus Macaque
Macaca mulatta
XP_001114794
1258
138636
A1005
P
P
E
P
P
S
P
A
R
A
P
V
P
P
A
Dog
Lupus familis
XP_542327
1264
138869
A1011
P
P
E
P
P
S
P
A
R
A
P
V
P
P
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9ES52
1191
133524
S972
P
P
S
Q
P
P
L
S
P
K
K
F
S
S
S
Rat
Rattus norvegicus
P97573
1190
133575
S971
P
P
S
Q
P
P
L
S
P
K
K
F
S
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520934
1019
113512
P818
S
L
D
R
T
Q
N
P
G
K
T
D
R
K
K
Chicken
Gallus gallus
XP_422567
1182
133482
P973
P
K
P
S
L
Q
T
P
V
S
R
S
I
C
N
Frog
Xenopus laevis
Q6P4S2
1019
115278
L818
Y
G
E
G
C
I
A
L
R
K
E
D
T
E
Q
Zebra Danio
Brachydanio rerio
Q2I6J1
1266
140353
A1010
K
P
P
S
G
S
S
A
Q
G
R
W
Q
T
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789838
1327
148052
S1043
P
M
S
A
T
P
M
S
A
D
P
M
D
G
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
77.8
41.3
40.9
N.A.
87.8
87.8
N.A.
38.7
68.2
56.5
43.1
N.A.
N.A.
N.A.
N.A.
31
Protein Similarity:
100
77.8
57.5
56.8
N.A.
92.1
92
N.A.
48.5
78.7
67.1
57.9
N.A.
N.A.
N.A.
N.A.
47.3
P-Site Identity:
100
13.3
26.6
26.6
N.A.
73.3
73.3
N.A.
6.6
6.6
6.6
13.3
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
100
26.6
40
40
N.A.
80
80
N.A.
13.3
26.6
13.3
33.3
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
10
10
28
10
19
0
0
0
0
19
% A
% Cys:
0
0
0
0
10
0
0
0
0
0
0
0
0
10
0
% C
% Asp:
0
0
10
0
0
0
0
0
0
10
0
19
10
0
10
% D
% Glu:
0
0
28
0
0
0
0
0
0
10
10
0
0
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
28
0
0
0
% F
% Gly:
0
10
19
10
10
0
0
0
10
10
0
0
0
10
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
10
10
0
0
0
0
0
10
0
0
% I
% Lys:
10
10
0
0
0
0
0
0
0
46
28
0
0
10
10
% K
% Leu:
0
10
0
10
10
0
19
10
0
0
0
0
10
0
0
% L
% Met:
0
10
0
0
0
0
10
0
0
0
0
10
0
0
0
% M
% Asn:
10
0
0
0
0
0
10
0
0
0
0
0
0
0
10
% N
% Pro:
64
55
19
19
55
37
19
19
28
0
28
0
28
28
0
% P
% Gln:
0
0
0
28
0
19
0
0
19
0
0
0
10
0
10
% Q
% Arg:
0
10
0
10
0
0
10
0
28
0
19
10
10
0
0
% R
% Ser:
10
0
28
19
0
28
10
37
0
10
10
10
19
28
37
% S
% Thr:
0
0
0
0
19
0
10
10
0
0
10
0
10
10
0
% T
% Val:
0
0
0
0
0
0
0
0
10
0
0
19
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% W
% Tyr:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _